Logical Analysis Report Key Focus Robertson and his colleagues, for instance, set out to reduce the six serine codons to just two. ... He and his colleagues set out to create Syn57, a version of E. coli with only 57 codons. ...
High Level Topics CODONS SYN57 SCIENTISTS High Level Abstractions CODONS ( CODONS ) top ( CODONS, COLLEAGUES ) top ( CODONS, COLLEAGUES, SYN57 ) top ( CODONS, COLLEAGUES, SERINE ) top ( CODONS, COLLEAGUES, NYERGES ) top ( CODONS, COLLEAGUES, HARVARD ) top ( CODONS, AMINO ) top ( CODONS, AMINO, TRIPLET ) top ( CODONS, AMINO, TCT ) top ( CODONS, AMINO, SERINE ) top ( CODONS, AMINO, CODON ) top ( CODONS, SERINE ) top ( CODONS, SERINE, TRIPLET ) top ( CODONS, SERINE, TCT ) top ( CODONS, WHITTLE ) top ( CODONS, TRIPLET ) top ( CODONS, TINKERING ) top ( CODONS, TCT ) top ( CODONS, SYN57 ) top SYN57 ( SYN57 ) top ( SYN57, MICROBE ) top ( SYN57, MICROBE, THREAT ) top ( SYN57, MICROBE, GIBBERISH ) top ( SYN57, MICROBE, DNA ) top ( SYN57, THREAT ) top ( SYN57, SYN61 ) top ( SYN57, STITCHING ) top ( SYN57, SCIENTISTS ) top ( SYN57, RISKS ) top ( SYN57, POTENTIAL ) top ( SYN57, POPULATION ) top SCIENTISTS ( SCIENTISTS ) top ( SCIENTISTS, RISKS ) top ( SCIENTISTS, POTENTIAL ) top ( SCIENTISTS, MOLECULES ) top ( SCIENTISTS, ENVIRONMENT ) top
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( CODONS ) top ( CODONS, COLLEAGUES ) top ( CODONS, COLLEAGUES, SYN57 ) top top He and his colleagues set out to create Syn57, a version of E. coli with only 57 codons. ( CODONS, COLLEAGUES, SERINE ) top top Robertson and his colleagues, for instance, set out to reduce the six serine codons to just two. ( CODONS, COLLEAGUES, NYERGES ) top top They entered a race with Dr. Nyerges and his colleagues at Harvard, who were already trying to reach that same goal ( CODONS, COLLEAGUES, HARVARD ) top top They entered a race with Dr. Nyerges and his colleagues at Harvard, who were already trying to reach that same goal. ( CODONS, AMINO ) top ( CODONS, AMINO, TRIPLET ) top top For instance, the triplet of bases TCT leads to the amino acid serine. But so do five other codons - TCC, TCA, TCG, AGT and AGC ( CODONS, AMINO, TCT ) top top For instance, the triplet of bases TCT leads to the amino acid serine. But so do five other codons - TCC, TCA, TCG, AGT and AGC ( CODONS, AMINO, SERINE ) top top For instance, the triplet of bases TCT leads to the amino acid serine. But so do five other codons - TCC, TCA, TCG, AGT and AGC. ( CODONS, AMINO, CODON ) top top To make the translation work, our cells read the bases three at a time, in units called codons. Each codon matches one of the 20 different amino acids that are available in the cell ( CODONS, SERINE ) top ( CODONS, SERINE, TRIPLET ) top top See ( CODONS , AMINO , TRIPLET ) ( CODONS, SERINE, TCT ) top top See ( CODONS , AMINO , TCT ) ( CODONS, WHITTLE ) top top coli with only 61 codons, which they named Syn61. Its ability to survive without three codons encouraged them to whittle its genetic code down even further. ( CODONS, TRIPLET ) top top See ( CODONS , AMINO , TRIPLET ) ( CODONS, TINKERING ) top top Both teams have been tinkering with Escherichia coli, a species of bacteria that dwells in the human gut and has been intensively studied for more than a century ( CODONS, TCT ) top top See ( CODONS , AMINO , TCT ) ( CODONS, SYN57 ) top top He and his colleagues set out to create Syn57, a version of E. coli with only 57 codons. They entered a race with Dr ( SYN57 ) top ( SYN57, MICROBE ) top ( SYN57, MICROBE, THREAT ) top top Then again, that spread would become a threat only if other bacteria could read the engineered gene and make proteins from it ( SYN57, MICROBE, GIBBERISH ) top top If the gene came from a microbe like Syn57, which used a different genetic code, it would be gibberish to natural microbes. ( SYN57, MICROBE, DNA ) top top They tested these changes by making small fragments of DNA and observing how well the microbe could read them. ( SYN57, THREAT ) top top See ( SYN57 , MICROBE , THREAT ) ( SYN57, SYN61 ) top top For Syn61, the researchers had altered more than 18,000 codons in E. coli's genome ( SYN57, STITCHING ) top top They are now working on stitching them together into a single molecule. "We will definitely get there," he said. ( SYN57, SCIENTISTS ) top top . Syn57 might also help scientists address the potential risks that could come if engineered microbes were released into the environment ( SYN57, RISKS ) top top . Syn57 might also help scientists address the potential risks that could come if engineered microbes were released into the environment ( SYN57, POTENTIAL ) top top . Syn57 might also help scientists address the potential risks that could come if engineered microbes were released into the environment ( SYN57, POPULATION ) top top Syn57 is unquestionably alive, but just barely. E. coli typically takes an hour to double its population; Syn57 needs four hours. ( SCIENTISTS ) top ( SCIENTISTS, RISKS ) top top That would enable bacteria to make new kinds of drugs or other useful molecules.. . Syn57 might also help scientists address the potential risks that could come if engineered microbes were released into the environment ( SCIENTISTS, POTENTIAL ) top top That would enable bacteria to make new kinds of drugs or other useful molecules.. . Syn57 might also help scientists address the potential risks that could come if engineered microbes were released into the environment ( SCIENTISTS, MOLECULES ) top top That would enable bacteria to make new kinds of drugs or other useful molecules.. . Syn57 might also help scientists address the potential risks that could come if engineered microbes were released into the environment ( SCIENTISTS, ENVIRONMENT ) top top Syn57 might also help scientists address the potential risks that could come if engineered microbes were released into the environment.